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Breaching the nuclear envelope in development and disease

In eukaryotic cells the nuclear genome is enclosed by the nuclear envelope (NE). In metazoans, the NE breaks down in mitosis and it has been assumed that the physical barrier separating nucleoplasm and cytoplasm remains intact during the rest of the cell cycle and cell differentiation. However, rece...

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Detalles Bibliográficos
Autores principales: Hatch, Emily, Hetzer, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003239/
https://www.ncbi.nlm.nih.gov/pubmed/24751535
http://dx.doi.org/10.1083/jcb.201402003

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