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A novel Netrin-1–sensitive mechanism promotes local SNARE-mediated exocytosis during axon branching
Developmental axon branching dramatically increases synaptic capacity and neuronal surface area. Netrin-1 promotes branching and synaptogenesis, but the mechanism by which Netrin-1 stimulates plasma membrane expansion is unknown. We demonstrate that SNARE-mediated exocytosis is a prerequisite for ax...
Autores principales: | Winkle, Cortney C., McClain, Leslie M., Valtschanoff, Juli G., Park, Charles S., Maglione, Christopher, Gupton, Stephanie L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003241/ https://www.ncbi.nlm.nih.gov/pubmed/24778312 http://dx.doi.org/10.1083/jcb.201311003 |
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