Distinct regulatory mechanisms balance DegP proteolysis to maintain cellular fitness during heat stress

Intracellular proteases combat proteotoxic stress by degrading damaged proteins, but their activity must be carefully controlled to maintain cellular fitness. The activity of Escherichia coli DegP, a highly conserved periplasmic protease, is regulated by substrate-dependent allosteric transformation...

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Detalles Bibliográficos
Autores principales: Kim, Seokhee, Sauer, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003281/
https://www.ncbi.nlm.nih.gov/pubmed/24736846
http://dx.doi.org/10.1101/gad.238394.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003281/
https://www.ncbi.nlm.nih.gov/pubmed/24736846
http://dx.doi.org/10.1101/gad.238394.114

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