Cargando…

Dosimetric characteristics of a new unit for electronic skin brachytherapy

PURPOSE: Brachytherapy with radioactive high dose rate (HDR) (192)Ir source is applied to small skin cancer lesions, using surface applicators, i.e. Leipzig or Valencia type. New developments in the field of radiotherapy for skin cancer include electronic brachytherapy. This technique involves the p...

Descripción completa

Detalles Bibliográficos
Autores principales: Garcia-Martinez, Teresa, Chan, Jan-Pieter, Perez-Calatayud, Jose, Ballester, Facundo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003426/
https://www.ncbi.nlm.nih.gov/pubmed/24790622
http://dx.doi.org/10.5114/jcb.2014.40770
_version_ 1782313847446568960
author Garcia-Martinez, Teresa
Chan, Jan-Pieter
Perez-Calatayud, Jose
Ballester, Facundo
author_facet Garcia-Martinez, Teresa
Chan, Jan-Pieter
Perez-Calatayud, Jose
Ballester, Facundo
author_sort Garcia-Martinez, Teresa
collection PubMed
description PURPOSE: Brachytherapy with radioactive high dose rate (HDR) (192)Ir source is applied to small skin cancer lesions, using surface applicators, i.e. Leipzig or Valencia type. New developments in the field of radiotherapy for skin cancer include electronic brachytherapy. This technique involves the placement of an HDR X-ray source close to the skin, therefore combining the benefits of brachytherapy with the reduced shielding requirements and targeted energy of low energy X-rays. Recently, the Esteya(®) Electronic Brachytherapy System (Esteya EBS, Elekta AB-Nucletron, Stockholm, Sweden) has been developed specifically for HDR brachytherapy treatment of surface lesions. The system provides radionuclide free HDR brachytherapy by means of a small 69.5 kV X-ray source. The purpose of this study is to obtain the dosimetric characterization required for clinical implementation, providing the detailed methodology to perform the commissioning. MATERIAL AND METHODS: Flatness, symmetry and penumbra, percentage of depth dose (PDD), kV stability, HVL, output, spectrum, linearity, and leakage have been evaluated for a set of applicators (from 10 mm to 30 mm in diameter). RESULTS: Flatness and symmetry resulted better than 5% with around 1 mm of penumbra. The depth dose gradient is about 7%/mm. A kV value of 68.4 ± 1.0 kV (k = 1) was obtained, in good agreement with manufacturer data (69.5 kV). HVL was 1.85 mm Al. Dose rate for a typical 6 Gy to 7 Gy prescription resulted about 3.3 Gy/min and the leakage value was < 100 µGy/min. CONCLUSIONS: The new Esteya(®) Electronic Brachytherapy System presents excellent flatness and penumbra as with the Valencia applicator case, combined with an improved PDD, allowing treatment of lesions of up to a depth of 5 mm in combination with reduced treatment duration. The Esteya unit allows HDR brachytherapy superficial treatment within a minimally shielded environment due its low energy.
format Online
Article
Text
id pubmed-4003426
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Termedia Publishing House
record_format MEDLINE/PubMed
spelling pubmed-40034262014-04-30 Dosimetric characteristics of a new unit for electronic skin brachytherapy Garcia-Martinez, Teresa Chan, Jan-Pieter Perez-Calatayud, Jose Ballester, Facundo J Contemp Brachytherapy Original Paper PURPOSE: Brachytherapy with radioactive high dose rate (HDR) (192)Ir source is applied to small skin cancer lesions, using surface applicators, i.e. Leipzig or Valencia type. New developments in the field of radiotherapy for skin cancer include electronic brachytherapy. This technique involves the placement of an HDR X-ray source close to the skin, therefore combining the benefits of brachytherapy with the reduced shielding requirements and targeted energy of low energy X-rays. Recently, the Esteya(®) Electronic Brachytherapy System (Esteya EBS, Elekta AB-Nucletron, Stockholm, Sweden) has been developed specifically for HDR brachytherapy treatment of surface lesions. The system provides radionuclide free HDR brachytherapy by means of a small 69.5 kV X-ray source. The purpose of this study is to obtain the dosimetric characterization required for clinical implementation, providing the detailed methodology to perform the commissioning. MATERIAL AND METHODS: Flatness, symmetry and penumbra, percentage of depth dose (PDD), kV stability, HVL, output, spectrum, linearity, and leakage have been evaluated for a set of applicators (from 10 mm to 30 mm in diameter). RESULTS: Flatness and symmetry resulted better than 5% with around 1 mm of penumbra. The depth dose gradient is about 7%/mm. A kV value of 68.4 ± 1.0 kV (k = 1) was obtained, in good agreement with manufacturer data (69.5 kV). HVL was 1.85 mm Al. Dose rate for a typical 6 Gy to 7 Gy prescription resulted about 3.3 Gy/min and the leakage value was < 100 µGy/min. CONCLUSIONS: The new Esteya(®) Electronic Brachytherapy System presents excellent flatness and penumbra as with the Valencia applicator case, combined with an improved PDD, allowing treatment of lesions of up to a depth of 5 mm in combination with reduced treatment duration. The Esteya unit allows HDR brachytherapy superficial treatment within a minimally shielded environment due its low energy. Termedia Publishing House 2014-02-19 2014-03 /pmc/articles/PMC4003426/ /pubmed/24790622 http://dx.doi.org/10.5114/jcb.2014.40770 Text en Copyright © 2014 Termedia http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Paper
Garcia-Martinez, Teresa
Chan, Jan-Pieter
Perez-Calatayud, Jose
Ballester, Facundo
Dosimetric characteristics of a new unit for electronic skin brachytherapy
title Dosimetric characteristics of a new unit for electronic skin brachytherapy
title_full Dosimetric characteristics of a new unit for electronic skin brachytherapy
title_fullStr Dosimetric characteristics of a new unit for electronic skin brachytherapy
title_full_unstemmed Dosimetric characteristics of a new unit for electronic skin brachytherapy
title_short Dosimetric characteristics of a new unit for electronic skin brachytherapy
title_sort dosimetric characteristics of a new unit for electronic skin brachytherapy
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003426/
https://www.ncbi.nlm.nih.gov/pubmed/24790622
http://dx.doi.org/10.5114/jcb.2014.40770
work_keys_str_mv AT garciamartinezteresa dosimetriccharacteristicsofanewunitforelectronicskinbrachytherapy
AT chanjanpieter dosimetriccharacteristicsofanewunitforelectronicskinbrachytherapy
AT perezcalatayudjose dosimetriccharacteristicsofanewunitforelectronicskinbrachytherapy
AT ballesterfacundo dosimetriccharacteristicsofanewunitforelectronicskinbrachytherapy