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Therapeutic potential of statins and the induction of heme oxygenase-1 in preeclampsia()
Heme oxygenase (Hmox) is an endogenous system that offers protection against placental cytotoxic damage associated with preeclampsia. The Hmox1/carbon monoxide (CO) pathway inhibits soluble Flt-1 (sFlt-1) and soluble Endoglin (sEng). More importantly, statins induce Hmox1 and suppress the release of...
Autores principales: | Ramma, Wenda, Ahmed, Asif |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier/North-Holland Biomedical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003533/ https://www.ncbi.nlm.nih.gov/pubmed/24503248 http://dx.doi.org/10.1016/j.jri.2013.12.120 |
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