Cargando…
Targeted Inhibition of mTOR Signaling Improves Sensitivity of Esophageal Squamous Cell Carcinoma Cells to Cisplatin
mTOR is an evolutionarily conserved serine-threonine kinase with a central role in cell growth, invasion, and metastasis of tumors, and is activated in many cancers. The aims of this study were to investigate the expression of mTOR in ESCC tissues and its relationship with progression of ESCC and me...
Autores principales: | Hou, Guiqin, Yang, Shuai, Zhou, Yuanyuan, Wang, Cong, Zhao, Wen, Lu, Zhaoming |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003759/ https://www.ncbi.nlm.nih.gov/pubmed/24818169 http://dx.doi.org/10.1155/2014/845763 |
Ejemplares similares
-
RICTOR/mTORC2 affects tumorigenesis and therapeutic efficacy of mTOR inhibitors in esophageal squamous cell carcinoma
por: Lu, Zhaoming, et al.
Publicado: (2020) -
LSD1 regulates Notch and PI3K/Akt/mTOR pathways through binding the promoter regions of Notch target genes in esophageal squamous cell carcinoma
por: Hou, Guiqin, et al.
Publicado: (2019) -
Ipriflavone Suppresses Growth of Esophageal Squamous Cell Carcinoma Through Inhibiting mTOR In Vitro and In Vivo
por: Shi, Xiaodan, et al.
Publicado: (2021) -
Ethyl Ferulate Suppresses Esophageal Squamous Cell Carcinoma Tumor Growth Through Inhibiting the mTOR Signaling Pathway
por: Pang, Mengjun, et al.
Publicado: (2022) -
Downregulation of p70S6K Enhances Cell Sensitivity to Rapamycin in Esophageal Squamous Cell Carcinoma
por: Lu, Zhaoming, et al.
Publicado: (2016)