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A Large French Case-Control Study Emphasizes the Role of Rare Mc1R Variants in Melanoma Risk
Background. The MC1R gene implicated in melanogenesis and skin pigmentation is highly polymorphic. Several alleles are associated with red hair and fair skin phenotypes and contribute to melanoma risk. Objective. This work aims to assess the effect of different classes of MC1R variants, notably rare...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003837/ https://www.ncbi.nlm.nih.gov/pubmed/24982914 http://dx.doi.org/10.1155/2014/925716 |