Quantitative Assessment of Heteroplasmy of Mitochondrial Genome: Perspectives in Diagnostics and Methodological Pitfalls

The role of alterations of mitochondrial DNA (mtDNA) in the development of human pathologies is not understood well. Most of mitochondrial mutations are characterized by the phenomenon of heteroplasmy which is defined as the presence of a mixture of more than one type of an organellar genome within...

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Detalles Bibliográficos
Autores principales: Sobenin, Igor A., Mitrofanov, Konstantin Y., Zhelankin, Andrey V., Sazonova, Margarita A., Postnov, Anton Y., Revin, Victor V., Bobryshev, Yuri V., Orekhov, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003915/
https://www.ncbi.nlm.nih.gov/pubmed/24818137
http://dx.doi.org/10.1155/2014/292017

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