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A Simple Small Size and Low Cost Sensor Based on Surface Plasmon Resonance for Selective Detection of Fe(III)

A simple, small size, and low cost sensor based on a Deferoxamine Self Assembled Monolayer (DFO-SAM) and Surface Plasmon Resonance (SPR) transduction, in connection with a Plastic Optical Fiber (POF), has been developed for the selective detection of Fe(III). DFO-SAM sensors based on appropriate ele...

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Autores principales: Cennamo, Nunzio, Alberti, Giancarla, Pesavento, Maria, D'Agostino, Girolamo, Quattrini, Federico, Biesuz, Raffaela, Zeni, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003962/
https://www.ncbi.nlm.nih.gov/pubmed/24608007
http://dx.doi.org/10.3390/s140304657
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author Cennamo, Nunzio
Alberti, Giancarla
Pesavento, Maria
D'Agostino, Girolamo
Quattrini, Federico
Biesuz, Raffaela
Zeni, Luigi
author_facet Cennamo, Nunzio
Alberti, Giancarla
Pesavento, Maria
D'Agostino, Girolamo
Quattrini, Federico
Biesuz, Raffaela
Zeni, Luigi
author_sort Cennamo, Nunzio
collection PubMed
description A simple, small size, and low cost sensor based on a Deferoxamine Self Assembled Monolayer (DFO-SAM) and Surface Plasmon Resonance (SPR) transduction, in connection with a Plastic Optical Fiber (POF), has been developed for the selective detection of Fe(III). DFO-SAM sensors based on appropriate electrochemical techniques can be frequently found in the scientific literature. In this work, we present the first example of a DFO-SAM sensor based on SPR in an optical fiber. The SPR sensing platform was realized by removing the cladding of a plastic optical fiber along half the circumference, spin coating a buffer of Microposit S1813 photoresist on the exposed core, and finally sputtering a thin gold film. The hydroxamate siderophore deferoxamine (DFO), having high binding affinity for Fe(III), is then used in its immobilized form, as self-assembled monolayer on the gold layer surface of the POF sensor. The results showed that the DFO-SAM-POF-sensor was able to sense the formation of the Fe(III)/DFO complex in the range of concentrations between 1 μm and 50 μm with a linearity range from 0 to 30 μm of Fe(III). The selectivity of the sensor was also proved by interference tests.
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spelling pubmed-40039622014-04-29 A Simple Small Size and Low Cost Sensor Based on Surface Plasmon Resonance for Selective Detection of Fe(III) Cennamo, Nunzio Alberti, Giancarla Pesavento, Maria D'Agostino, Girolamo Quattrini, Federico Biesuz, Raffaela Zeni, Luigi Sensors (Basel) Article A simple, small size, and low cost sensor based on a Deferoxamine Self Assembled Monolayer (DFO-SAM) and Surface Plasmon Resonance (SPR) transduction, in connection with a Plastic Optical Fiber (POF), has been developed for the selective detection of Fe(III). DFO-SAM sensors based on appropriate electrochemical techniques can be frequently found in the scientific literature. In this work, we present the first example of a DFO-SAM sensor based on SPR in an optical fiber. The SPR sensing platform was realized by removing the cladding of a plastic optical fiber along half the circumference, spin coating a buffer of Microposit S1813 photoresist on the exposed core, and finally sputtering a thin gold film. The hydroxamate siderophore deferoxamine (DFO), having high binding affinity for Fe(III), is then used in its immobilized form, as self-assembled monolayer on the gold layer surface of the POF sensor. The results showed that the DFO-SAM-POF-sensor was able to sense the formation of the Fe(III)/DFO complex in the range of concentrations between 1 μm and 50 μm with a linearity range from 0 to 30 μm of Fe(III). The selectivity of the sensor was also proved by interference tests. MDPI 2014-03-07 /pmc/articles/PMC4003962/ /pubmed/24608007 http://dx.doi.org/10.3390/s140304657 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Cennamo, Nunzio
Alberti, Giancarla
Pesavento, Maria
D'Agostino, Girolamo
Quattrini, Federico
Biesuz, Raffaela
Zeni, Luigi
A Simple Small Size and Low Cost Sensor Based on Surface Plasmon Resonance for Selective Detection of Fe(III)
title A Simple Small Size and Low Cost Sensor Based on Surface Plasmon Resonance for Selective Detection of Fe(III)
title_full A Simple Small Size and Low Cost Sensor Based on Surface Plasmon Resonance for Selective Detection of Fe(III)
title_fullStr A Simple Small Size and Low Cost Sensor Based on Surface Plasmon Resonance for Selective Detection of Fe(III)
title_full_unstemmed A Simple Small Size and Low Cost Sensor Based on Surface Plasmon Resonance for Selective Detection of Fe(III)
title_short A Simple Small Size and Low Cost Sensor Based on Surface Plasmon Resonance for Selective Detection of Fe(III)
title_sort simple small size and low cost sensor based on surface plasmon resonance for selective detection of fe(iii)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003962/
https://www.ncbi.nlm.nih.gov/pubmed/24608007
http://dx.doi.org/10.3390/s140304657
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