Cargando…

Decreased response to IL-12 and IL-18 of peripheral blood cells in rheumatoid arthritis

Inflamed synovium of rheumatoid arthritis (RA) has been associated with a T helper (Th)1 cytokine profile but the blood situation remains to be clarified. We studied the differential IFN-γ producing activity of peripheral blood mononuclear cells (PBMCs) from RA patients (RA-PBMCs) and from healthy c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kawashima, Masanori, Miossec, Pierre
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2004
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC400411/ https://www.ncbi.nlm.nih.gov/pubmed/14979936 http://dx.doi.org/10.1186/ar1020

Ejemplares similares

IL-17, synoviolin and rheumatoid arthritis chronicity
por: Miossec, Pierre
Publicado: (2012)

IL-17 in Rheumatoid Arthritis and Precision Medicine: From Synovitis Expression to Circulating Bioactive Levels
por: Robert, Marie, et al.
Publicado: (2019)

Defect of Th1 immune response of whole blood cells from active patients with rheumatoid arthritis (RA)
por: Kawashima, M, et al.
Publicado: (2003)

IL-1 but not IL-18 induces osteoprotegerin and TRAIL in rheumatoid arthritis synovial fibroblasts
por: Morel, J, et al.
Publicado: (2003)

IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis
por: Chabaud, Martine, et al.
Publicado: (2001)

Effect of IL-34 on T helper 17 cell proliferation and IL-17 secretion by peripheral blood mononuclear cells from rheumatoid arthritis patients
por: Li, Xin, et al.
Publicado: (2020)

Synergistic Interaction Between High Bioactive IL-17A and Joint Destruction for the Occurrence of Cardiovascular Events in Rheumatoid Arthritis
por: Robert, Marie, et al.
Publicado: (2020)

Effect of IL-18 on synovial cell subsets and its regulation by IL-18BP
por: Kawashima, M, et al.
Publicado: (2002)

Inhibition of the IL-18 Receptor Signaling Pathway Ameliorates Disease in a Murine Model of Rheumatoid Arthritis
por: Nozaki, Yuji, et al.
Publicado: (2019)

Additive or Synergistic Interactions Between IL-17A or IL-17F and TNF or IL-1β Depend on the Cell Type
por: Noack, Mélissa, et al.
Publicado: (2019)

Dysregulated Serum IL-23 and SIRT1 Activity in Peripheral Blood Mononuclear Cells of Patients with Rheumatoid Arthritis
por: Wendling, Daniel, et al.
Publicado: (2015)

Increased AP-1 and NF-κB activation and recruitment with the combination of the proinflammatory cytokines IL-1β, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocytes
por: Granet, Corinne, et al.
Publicado: (2004)

IL-18 blockade is a potential disease-modifying therapy for rheumatoid arthritis
por: Plater-Zyberk, C, et al.
Publicado: (2001)

IL-18 correlates positively with CRP and IL-1Ra but not with DAS28 or bone erosion in patients with rheumatoid arthritis
por: Nielsen, H, et al.
Publicado: (2002)

The Effect of Homocysteine on the Secretion of Il-1β, Il-6, Il-10, Il-12 and RANTES by Peripheral Blood Mononuclear Cells—An In Vitro Study
por: Borowska, Magdalena, et al.
Publicado: (2021)

Synoviocytes and skin fibroblasts show opposite effects on IL-23 production and IL-23 receptor expression during cell interactions with immune cells
por: Noack, Mélissa, et al.
Publicado: (2022)

IL-6 pathway-driven investigation of response to IL-6 receptor inhibition in rheumatoid arthritis
por: Wang, Jianmei, et al.
Publicado: (2013)

Peripheral Blood MDSCs, IL-10 and IL-12 in Children with Asthma and Their Importance in Asthma Development
por: Zhang, Yan-Li, et al.
Publicado: (2013)

Association Between IL-17, IL-8 and IL-18 Expression in Peripheral Blood and Helicobacter Pylori Infection in Mongolian Gerbils
por: Zhao, Yan-Rong, et al.
Publicado: (2015)

IL-12, IL-6 and IFN-gamma production by lymphocytes of pregnant women with rheumatoid arthritis remission during pregnancy.
por: Tchórzewski, H, et al.
Publicado: (2000)

IL-15 and its role in rheumatoid arthritis
por: Kurowska-Stolarska, M, et al.
Publicado: (2003)

IL-26 Kick-Starts Rheumatoid Arthritis
por: Sedwick, Caitlin
Publicado: (2012)

Circulating levels of IL-7 in rheumatoid arthritis
por: Churchman, S, et al.
Publicado: (2007)

Promotion of osteoclastogenesis by IL-26 in rheumatoid arthritis
por: Lee, Kyung-Ann, et al.
Publicado: (2019)

Pathogenic roles of IL-6 and IL-6 blocking therapy on rheumatoid arthritis
por: Yoshizaki, K, et al.
Publicado: (2003)

IL-18 binding protein suppresses IL-17-induced osteoclastogenesis and rectifies type 17 helper T cell / regulatory T cell imbalance in rheumatoid arthritis
por: Min, Hong Ki, et al.
Publicado: (2021)

IL-18 expression in synovial biopsies of patients with active rheumatoid arthritis is associated with enhanced levels of both IL-1 and TNFα
por: Joosten, LAB, et al.
Publicado: (2002)

Introduction: ‘Why is there persistent disease despite aggressive therapy of rheumatoid arthritis?’
por: Miossec, Pierre
Publicado: (2014)

Predicting treatment response to IL6R blockers in rheumatoid arthritis
por: Nouri, Bako, et al.
Publicado: (2020)

Soluble IL-18 receptor complex: a new star in the firmament of rheumatoid arthritis diagnosis?
por: van de Loo, Fons AJ
Publicado: (2011)

Promoter polymorphisms in the IL-18 gene are associated with rheumatoid arthritis in two independent clinical cohorts
por: Gracie, JA, et al.
Publicado: (2003)

The role of IL-18 in addition to Th17 cytokines in rheumatoid arthritis development and treatment in women
por: Vasilev, Georgi, et al.
Publicado: (2021)

IL-17A and TNF-α Increase the Expression of the Antiapoptotic Adhesion Molecule Amigo-2 in Arthritis Synoviocytes
por: Benedetti, Giulia, et al.
Publicado: (2016)

IL-12 and IL-18 Induction and Subsequent NKT Activation Effects of the Japanese Botanical Medicine Juzentaihoto
por: Fujiki, Kazuhiko, et al.
Publicado: (2008)

Oncolytic adenovirus co-expressing IL-12 and IL-18 improves tumor-specific immunity via differentiation of T cells expressing IL-12Rβ(2) or IL-18Rα
por: Choi, I-K, et al.
Publicado: (2011)

Oncolytic adenovirus co-expressing IL-12 and IL-18 improves tumor-specific immunity via differentiation of T cells expressing IL-12Rβ(2) or IL-18Rα
por: Choi, I-K, et al.
Publicado: (2011)

IL-32 and IL-17 interact and have the potential to aggravate osteoclastogenesis in rheumatoid arthritis
por: Moon, Young-Mee, et al.
Publicado: (2012)

IL17A and IL17F gene polymorphisms in patients with rheumatoid arthritis
por: Pawlik, Andrzej, et al.
Publicado: (2016)

The Relationship of Cytokines IL-13 and IL-17 with Autoantibodies Profile in Early Rheumatoid Arthritis
por: Siloşi, Isabela, et al.
Publicado: (2016)

Intracerebral administration of Interleukin-12 (IL-12) and IL-18 modifies the course of mouse scrapie
por: Pasquali, Paolo, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_3p5moe6qj45qf3tfknj7qv9rqu