Cargando…
Chondrocyte response to growth factors is modulated by p38 mitogen-activated protein kinase inhibition
Inhibitors of p38 mitogen-activated protein kinase (MAPK) diminish inflammatory arthritis in experimental animals. This may be effected by diminishing the production of inflammatory mediators, but this kinase is also part of the IL-1 signal pathway in articular chondrocytes. We determined the effect...
Autores principales: | Studer, Rebecca K, Bergman, Rachel, Stubbs, Tiffany, Decker, Kimberly |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC400413/ https://www.ncbi.nlm.nih.gov/pubmed/14979938 http://dx.doi.org/10.1186/ar1022 |
Ejemplares similares
-
P38 mitogen-activated protein kinase promotes dedifferentiation of primary articular chondrocytes in monolayer culture
por: Rosenzweig, Derek H, et al.
Publicado: (2013) -
CD95-induced osteoarthritic chondrocyte apoptosis and necrosis: dependency on p38 mitogen-activated protein kinase
por: Wei, Lei, et al.
Publicado: (2006) -
TNF-alpha induced chondrocyte apoptosis in NF-κB suppression is augmented by inhibition of p38 mitogen-activated protein kinase or phosphatidylinositol 3-kinase
por: Kim, H
Publicado: (2003) -
The case for inhibiting p38 mitogen-activated protein kinase in heart failure
por: Arabacilar, Pelin, et al.
Publicado: (2015) -
Redox-dependent dimerization of p38α mitogen-activated protein kinase with mitogen-activated protein kinase kinase 3
por: Bassi, Rekha, et al.
Publicado: (2017)