Possible effects of EXT2 on mesenchymal differentiation - lessons from the zebrafish

BACKGROUND: Mutations in the EXT genes disrupt polymerisation of heparan sulphates (HS) and lead to the development of osteochondroma, an isolated/sporadic- or a multifocal/hereditary cartilaginous bone tumour. Zebrafish (Danio rerio) is a very powerful animal model which has shown to present the sa...

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Detalles Bibliográficos
Autores principales: Wiweger, Malgorzata I, de Andrea, Carlos E, Scheepstra, Karel W F, Zhao, Zhe, Hogendoorn, Pancras C W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004154/
https://www.ncbi.nlm.nih.gov/pubmed/24628984
http://dx.doi.org/10.1186/1750-1172-9-35

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