Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis

Antibodies directed to citrullinated proteins (anti-cyclic citrullinated peptide) are highly specific for rheumatoid arthritis (RA). Recent data suggest that the antibodies may be involved in the disease process of RA and that several RA-associated genetic factors might be functionally linked to RA...

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Detalles Bibliográficos
Autores principales: Vossenaar, Erik R, Zendman, Albert JW, van Venrooij, Walther J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC400418/
https://www.ncbi.nlm.nih.gov/pubmed/14979924
http://dx.doi.org/10.1186/ar1027
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author Vossenaar, Erik R
Zendman, Albert JW
van Venrooij, Walther J
author_facet Vossenaar, Erik R
Zendman, Albert JW
van Venrooij, Walther J
author_sort Vossenaar, Erik R
collection PubMed
description Antibodies directed to citrullinated proteins (anti-cyclic citrullinated peptide) are highly specific for rheumatoid arthritis (RA). Recent data suggest that the antibodies may be involved in the disease process of RA and that several RA-associated genetic factors might be functionally linked to RA via modulation of the production of anti-cyclic citrullinated peptide antibodies or citrullinated antigens.
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spelling pubmed-4004182004-04-30 Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis Vossenaar, Erik R Zendman, Albert JW van Venrooij, Walther J Arthritis Res Ther Commentary Antibodies directed to citrullinated proteins (anti-cyclic citrullinated peptide) are highly specific for rheumatoid arthritis (RA). Recent data suggest that the antibodies may be involved in the disease process of RA and that several RA-associated genetic factors might be functionally linked to RA via modulation of the production of anti-cyclic citrullinated peptide antibodies or citrullinated antigens. BioMed Central 2004 2003-11-25 /pmc/articles/PMC400418/ /pubmed/14979924 http://dx.doi.org/10.1186/ar1027 Text en Copyright © 2004 BioMed Central Ltd
spellingShingle Commentary
Vossenaar, Erik R
Zendman, Albert JW
van Venrooij, Walther J
Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis
title Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis
title_full Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis
title_fullStr Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis
title_full_unstemmed Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis
title_short Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis
title_sort citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC400418/
https://www.ncbi.nlm.nih.gov/pubmed/14979924
http://dx.doi.org/10.1186/ar1027
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AT zendmanalbertjw citrullinationapossiblefunctionallinkbetweensusceptibilitygenesandrheumatoidarthritis
AT vanvenrooijwaltherj citrullinationapossiblefunctionallinkbetweensusceptibilitygenesandrheumatoidarthritis

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