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Biosynthesis of a Thiamin Antivitamin in Clostridium botulinum

[Image: see text] Bacimethrin-derived 2′-methoxythiamin pyrophosphate inhibits microbial growth by disrupting metabolic pathways dependent on thiamin-utilizing enzymes. This study describes the discovery of the bacimethrin biosynthetic gene cluster of Clostridium botulinum A ATCC 19397 and in vitro...

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Detalles Bibliográficos
Autores principales:	Cooper, Lisa E., O’Leary, Seán E., Begley, Tadhg P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004229/ https://www.ncbi.nlm.nih.gov/pubmed/24654570 http://dx.doi.org/10.1021/bi500281a

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