Natural killer cells and autoimmunity

Autoimmune diseases are often characterized as clinical syndromes caused by the inappropriate activation of T or B cells resulting in systemic or organ-specific damage. However, studies support a role for the innate immune system, and in particular natural killer (NK) cells, in stimulating or suppre...

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Detalles Bibliográficos
Autores principales: French, Anthony R, Yokoyama, Wayne M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC400423/
https://www.ncbi.nlm.nih.gov/pubmed/14979926
http://dx.doi.org/10.1186/ar1034
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author French, Anthony R
Yokoyama, Wayne M
author_facet French, Anthony R
Yokoyama, Wayne M
author_sort French, Anthony R
collection PubMed
description Autoimmune diseases are often characterized as clinical syndromes caused by the inappropriate activation of T or B cells resulting in systemic or organ-specific damage. However, studies support a role for the innate immune system, and in particular natural killer (NK) cells, in stimulating or suppressing autoimmunity. This review focuses on recent research elucidating a potential immunoregulatory role for NK cells in modulating T and B cell-mediated autoimmunity.
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spelling pubmed-4004232004-04-30 Natural killer cells and autoimmunity French, Anthony R Yokoyama, Wayne M Arthritis Res Ther Review Autoimmune diseases are often characterized as clinical syndromes caused by the inappropriate activation of T or B cells resulting in systemic or organ-specific damage. However, studies support a role for the innate immune system, and in particular natural killer (NK) cells, in stimulating or suppressing autoimmunity. This review focuses on recent research elucidating a potential immunoregulatory role for NK cells in modulating T and B cell-mediated autoimmunity. BioMed Central 2004 2003-12-09 /pmc/articles/PMC400423/ /pubmed/14979926 http://dx.doi.org/10.1186/ar1034 Text en Copyright © 2004 BioMed Central Ltd
spellingShingle Review
French, Anthony R
Yokoyama, Wayne M
Natural killer cells and autoimmunity
title Natural killer cells and autoimmunity
title_full Natural killer cells and autoimmunity
title_fullStr Natural killer cells and autoimmunity
title_full_unstemmed Natural killer cells and autoimmunity
title_short Natural killer cells and autoimmunity
title_sort natural killer cells and autoimmunity
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC400423/
https://www.ncbi.nlm.nih.gov/pubmed/14979926
http://dx.doi.org/10.1186/ar1034
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