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Cysteine Scanning Mutagenesis of Transmembrane Domain 10 in Organic Anion Transporting Polypeptide 1B1

[Image: see text] Organic anion transporting polypeptide (OATP) 1B1 is an important drug transporter expressed in human hepatocytes. Previous studies have indicated that transmembrane (TM) domain 2, 6, 8, 9, and in particular 10 might be part of the substrate binding site/translocation pathway. To e...

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Detalles Bibliográficos
Autores principales:	Ohnishi, Shuichi, Hays, Amanda, Hagenbuch, Bruno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004239/ https://www.ncbi.nlm.nih.gov/pubmed/24673529 http://dx.doi.org/10.1021/bi500176e

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