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OGlcNAcylation and Phosphorylation Have Opposing Structural Effects in tau: Phosphothreonine Induces Particular Conformational Order
[Image: see text] Phosphorylation and OGlcNAcylation are dynamic intracellular protein post-translational modifications that frequently are alternatively observed on the same serine and threonine residues. Phosphorylation and OGlcNAcylation commonly occur in natively disordered regions of proteins,...
Autores principales: | Brister, Michael A., Pandey, Anil K., Bielska, Agata A., Zondlo, Neal J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004249/ https://www.ncbi.nlm.nih.gov/pubmed/24559475 http://dx.doi.org/10.1021/ja407156m |
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