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Multiple functions for CD28 and cytotoxic T lymphocyte antigen-4 during different phases of T cell responses: implications for arthritis and autoimmune diseases

Chronic T cell responses, as they occur in rheumatoid arthritis, are complex and are likely to involve many mechanisms. There is a growing body of evidence that, in concert with the T cell antigen receptor signal, CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4; CD152) are the primary regulators o...

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Detalles Bibliográficos
Autores principales: Brunner-Weinzierl, Monika C, Hoff, Holger, Burmester, Gerd-R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC400439/
https://www.ncbi.nlm.nih.gov/pubmed/15059264
http://dx.doi.org/10.1186/ar1158