Interleukin-17 Retinotoxicity Is Prevented by Gene Transfer of a Soluble Interleukin-17 Receptor Acting as a Cytokine Blocker: Implications for Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is a common yet complex retinal degeneration that causes irreversible central blindness in the elderly. Pathology is widely believed to follow loss of retinal pigment epithelium (RPE) and photoreceptor degeneration. Here we report aberrant expression of interle...

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Detalles Bibliográficos
Autores principales: Ardeljan, Daniel, Wang, Yujuan, Park, Stanley, Shen, Defen, Chu, Xi Kathy, Yu, Cheng-Rong, Abu-Asab, Mones, Tuo, Jingsheng, Eberhart, Charles G., Olsen, Timothy W., Mullins, Robert F., White, Gary, Wadsworth, Sam, Scaria, Abraham, Chan, Chi-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004582/
https://www.ncbi.nlm.nih.gov/pubmed/24780906
http://dx.doi.org/10.1371/journal.pone.0095900

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