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Nonenzymatic domains of Kalirin7 contribute to spine morphogenesis through interactions with phosphoinositides and Abl

Like several Rho GDP/GTP exchange factors (GEFs), Kalirin7 (Kal7) contains an N-terminal Sec14 domain and multiple spectrin repeats. A natural splice variant of Kalrn lacking the Sec14 domain and four spectrin repeats is unable to increase spine formation; our goal was to understand the function of...

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Detalles Bibliográficos
Autores principales:	Ma, Xin-Ming, Miller, Megan B., Vishwanatha, K. S., Gross, Maegan J., Wang, Yanping, Abbott, Thomas, Lam, TuKiet T., Mains, Richard E., Eipper, Betty A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004595/ https://www.ncbi.nlm.nih.gov/pubmed/24600045 http://dx.doi.org/10.1091/mbc.E13-04-0215

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