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Rab35, acting through ACAP2 switching off Arf6, negatively regulates oligodendrocyte differentiation and myelination
Oligodendrocyte precursor cells differentiate to produce myelin sheaths that insulate axons to ensure fast propagation of action potentials. Many aspects of differentiation are regulated by multiple extracellular signals. However, their intracellular signalings remain elusive. We show that Rab35 and...
Autores principales: | Miyamoto, Yuki, Yamamori, Natsuki, Torii, Tomohiro, Tanoue, Akito, Yamauchi, Junji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004601/ https://www.ncbi.nlm.nih.gov/pubmed/24600047 http://dx.doi.org/10.1091/mbc.E13-10-0600 |
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