Cargando…
Development of an open source software module for enhanced visualization during MR-guided interstitial gynecologic brachytherapy
In 2010, gynecologic malignancies were the 4th leading cause of death in U.S. women and for patients with extensive primary or recurrent disease, treatment with interstitial brachytherapy may be an option. However, brachytherapy requires precise insertion of hollow catheters with introducers into th...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004789/ https://www.ncbi.nlm.nih.gov/pubmed/24790816 http://dx.doi.org/10.1186/2193-1801-3-167 |
_version_ | 1782314011377795072 |
---|---|
author | Chen, Xiaojun Egger, Jan |
author_facet | Chen, Xiaojun Egger, Jan |
author_sort | Chen, Xiaojun |
collection | PubMed |
description | In 2010, gynecologic malignancies were the 4th leading cause of death in U.S. women and for patients with extensive primary or recurrent disease, treatment with interstitial brachytherapy may be an option. However, brachytherapy requires precise insertion of hollow catheters with introducers into the tumor in order to eradicate the cancer. In this study, a software solution to assist interstitial gynecologic brachytherapy has been investigated and the software has been realized as an own module under (3D) Slicer, which is a free open source software platform for (translational) biomedical research. The developed research module allows on-time processing of intra-operative magnetic resonance imaging (iMRI) data over a direct DICOM connection to a MR scanner. Afterwards follows a multi-stage registration of CAD models of the medical brachytherapy devices (template, obturator) to the patient’s MR images, enabling the virtual placement of interstitial needles to assist the physician during the intervention. |
format | Online Article Text |
id | pubmed-4004789 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-40047892014-04-30 Development of an open source software module for enhanced visualization during MR-guided interstitial gynecologic brachytherapy Chen, Xiaojun Egger, Jan Springerplus Research In 2010, gynecologic malignancies were the 4th leading cause of death in U.S. women and for patients with extensive primary or recurrent disease, treatment with interstitial brachytherapy may be an option. However, brachytherapy requires precise insertion of hollow catheters with introducers into the tumor in order to eradicate the cancer. In this study, a software solution to assist interstitial gynecologic brachytherapy has been investigated and the software has been realized as an own module under (3D) Slicer, which is a free open source software platform for (translational) biomedical research. The developed research module allows on-time processing of intra-operative magnetic resonance imaging (iMRI) data over a direct DICOM connection to a MR scanner. Afterwards follows a multi-stage registration of CAD models of the medical brachytherapy devices (template, obturator) to the patient’s MR images, enabling the virtual placement of interstitial needles to assist the physician during the intervention. Springer International Publishing 2014-03-31 /pmc/articles/PMC4004789/ /pubmed/24790816 http://dx.doi.org/10.1186/2193-1801-3-167 Text en © Chen and Egger; licensee Springer. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. |
spellingShingle | Research Chen, Xiaojun Egger, Jan Development of an open source software module for enhanced visualization during MR-guided interstitial gynecologic brachytherapy |
title | Development of an open source software module for enhanced visualization during MR-guided interstitial gynecologic brachytherapy |
title_full | Development of an open source software module for enhanced visualization during MR-guided interstitial gynecologic brachytherapy |
title_fullStr | Development of an open source software module for enhanced visualization during MR-guided interstitial gynecologic brachytherapy |
title_full_unstemmed | Development of an open source software module for enhanced visualization during MR-guided interstitial gynecologic brachytherapy |
title_short | Development of an open source software module for enhanced visualization during MR-guided interstitial gynecologic brachytherapy |
title_sort | development of an open source software module for enhanced visualization during mr-guided interstitial gynecologic brachytherapy |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004789/ https://www.ncbi.nlm.nih.gov/pubmed/24790816 http://dx.doi.org/10.1186/2193-1801-3-167 |
work_keys_str_mv | AT chenxiaojun developmentofanopensourcesoftwaremoduleforenhancedvisualizationduringmrguidedinterstitialgynecologicbrachytherapy AT eggerjan developmentofanopensourcesoftwaremoduleforenhancedvisualizationduringmrguidedinterstitialgynecologicbrachytherapy |