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Preclinical evaluation of marketed sodium channel blockers in a rat model of myotonia discloses promising antimyotonic drugs
Although the sodium channel blocker mexiletine is considered the first-line drug in myotonia, some patients experiment adverse effects, while others do not gain any benefit. Other antimyotonic drugs are thus needed to offer mexiletine alternatives. In the present study, we used a previously-validate...
Autores principales: | Desaphy, Jean-François, Carbonara, Roberta, Costanza, Teresa, Conte Camerino, Diana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004800/ https://www.ncbi.nlm.nih.gov/pubmed/24613829 http://dx.doi.org/10.1016/j.expneurol.2014.02.023 |
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