Diprenylated Indole Alkaloids from Fruits of Hexalobus monopetalus

New hexalobine type alkaloid, 5-(2″,3″-epoxy-3″-methylbutyl)-3-(3′-hydroxy-3′-methyl-1′-acetyloxy-but-2′-yl)indole (1) alongside the known hexalobines 3-(2′,3′-dihydroxy-3′-methylbutyl)-5-(3″-methylcrotonoyl) indole (2), 3,5-hexalobine C (3) and 3,5-hexalobine D (4) were isolated from fruits of Hexa...

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Detalles Bibliográficos
Autores principales: Malebo, Hamisi M., Jonker, Stephan A., Waibel, Reiner, Nkunya, Mayunga H. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004831/
https://www.ncbi.nlm.nih.gov/pubmed/24859178
http://dx.doi.org/10.1007/s13659-014-0010-x
Descripción
Sumario:New hexalobine type alkaloid, 5-(2″,3″-epoxy-3″-methylbutyl)-3-(3′-hydroxy-3′-methyl-1′-acetyloxy-but-2′-yl)indole (1) alongside the known hexalobines 3-(2′,3′-dihydroxy-3′-methylbutyl)-5-(3″-methylcrotonoyl) indole (2), 3,5-hexalobine C (3) and 3,5-hexalobine D (4) were isolated from fruits of Hexalobus monopetalus. Compounds 3 and 4 exhibited antifungal activity against Candida albicans.

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