Diprenylated Indole Alkaloids from Fruits of Hexalobus monopetalus

New hexalobine type alkaloid, 5-(2″,3″-epoxy-3″-methylbutyl)-3-(3′-hydroxy-3′-methyl-1′-acetyloxy-but-2′-yl)indole (1) alongside the known hexalobines 3-(2′,3′-dihydroxy-3′-methylbutyl)-5-(3″-methylcrotonoyl) indole (2), 3,5-hexalobine C (3) and 3,5-hexalobine D (4) were isolated from fruits of Hexa...

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Autores principales: Malebo, Hamisi M., Jonker, Stephan A., Waibel, Reiner, Nkunya, Mayunga H. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004831/
https://www.ncbi.nlm.nih.gov/pubmed/24859178
http://dx.doi.org/10.1007/s13659-014-0010-x
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author Malebo, Hamisi M.
Jonker, Stephan A.
Waibel, Reiner
Nkunya, Mayunga H. H.
author_facet Malebo, Hamisi M.
Jonker, Stephan A.
Waibel, Reiner
Nkunya, Mayunga H. H.
author_sort Malebo, Hamisi M.
collection PubMed
description New hexalobine type alkaloid, 5-(2″,3″-epoxy-3″-methylbutyl)-3-(3′-hydroxy-3′-methyl-1′-acetyloxy-but-2′-yl)indole (1) alongside the known hexalobines 3-(2′,3′-dihydroxy-3′-methylbutyl)-5-(3″-methylcrotonoyl) indole (2), 3,5-hexalobine C (3) and 3,5-hexalobine D (4) were isolated from fruits of Hexalobus monopetalus. Compounds 3 and 4 exhibited antifungal activity against Candida albicans.
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spelling pubmed-40048312014-05-07 Diprenylated Indole Alkaloids from Fruits of Hexalobus monopetalus Malebo, Hamisi M. Jonker, Stephan A. Waibel, Reiner Nkunya, Mayunga H. H. Nat Prod Bioprospect Original Article New hexalobine type alkaloid, 5-(2″,3″-epoxy-3″-methylbutyl)-3-(3′-hydroxy-3′-methyl-1′-acetyloxy-but-2′-yl)indole (1) alongside the known hexalobines 3-(2′,3′-dihydroxy-3′-methylbutyl)-5-(3″-methylcrotonoyl) indole (2), 3,5-hexalobine C (3) and 3,5-hexalobine D (4) were isolated from fruits of Hexalobus monopetalus. Compounds 3 and 4 exhibited antifungal activity against Candida albicans. Springer Berlin Heidelberg 2014-04-02 /pmc/articles/PMC4004831/ /pubmed/24859178 http://dx.doi.org/10.1007/s13659-014-0010-x Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ This article is published under license to BioMed Central Ltd. Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Original Article
Malebo, Hamisi M.
Jonker, Stephan A.
Waibel, Reiner
Nkunya, Mayunga H. H.
Diprenylated Indole Alkaloids from Fruits of Hexalobus monopetalus
title Diprenylated Indole Alkaloids from Fruits of Hexalobus monopetalus
title_full Diprenylated Indole Alkaloids from Fruits of Hexalobus monopetalus
title_fullStr Diprenylated Indole Alkaloids from Fruits of Hexalobus monopetalus
title_full_unstemmed Diprenylated Indole Alkaloids from Fruits of Hexalobus monopetalus
title_short Diprenylated Indole Alkaloids from Fruits of Hexalobus monopetalus
title_sort diprenylated indole alkaloids from fruits of hexalobus monopetalus
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004831/
https://www.ncbi.nlm.nih.gov/pubmed/24859178
http://dx.doi.org/10.1007/s13659-014-0010-x
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