Hypercohones D–G, New Polycyclic Polyprenylated Acylphloroglucinol Type Natural Products from Hypericum cohaerens

Four new polycyclic polyprenylated acylphloroglucinol type metabolites, hypercohones D–G (1–4), along with four known analogues (5–8), were isolated from the aerial parts of Hypericum cohaerens. The structures of these isolates were elucidated by extensive spectroscopic methods. The inhibitory activ...

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Detalles Bibliográficos
Autores principales: Zhang, Jing-Jing, Yang, Xing-Wei, Ma, Jun-Zeng, Liu, Xia, Yang, Li-Xin, Yang, Sheng-Chao, Xu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004852/
https://www.ncbi.nlm.nih.gov/pubmed/24859375
http://dx.doi.org/10.1007/s13659-014-0007-5
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author Zhang, Jing-Jing
Yang, Xing-Wei
Ma, Jun-Zeng
Liu, Xia
Yang, Li-Xin
Yang, Sheng-Chao
Xu, Gang
author_facet Zhang, Jing-Jing
Yang, Xing-Wei
Ma, Jun-Zeng
Liu, Xia
Yang, Li-Xin
Yang, Sheng-Chao
Xu, Gang
author_sort Zhang, Jing-Jing
collection PubMed
description Four new polycyclic polyprenylated acylphloroglucinol type metabolites, hypercohones D–G (1–4), along with four known analogues (5–8), were isolated from the aerial parts of Hypericum cohaerens. The structures of these isolates were elucidated by extensive spectroscopic methods. The inhibitory activities of these isolates against five human cancer cell lines in vitro were also tested. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s13659-014-0007-5) contains supplementary material, which is available to authorized users.
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spelling pubmed-40048522014-05-07 Hypercohones D–G, New Polycyclic Polyprenylated Acylphloroglucinol Type Natural Products from Hypericum cohaerens Zhang, Jing-Jing Yang, Xing-Wei Ma, Jun-Zeng Liu, Xia Yang, Li-Xin Yang, Sheng-Chao Xu, Gang Nat Prod Bioprospect Original Article Four new polycyclic polyprenylated acylphloroglucinol type metabolites, hypercohones D–G (1–4), along with four known analogues (5–8), were isolated from the aerial parts of Hypericum cohaerens. The structures of these isolates were elucidated by extensive spectroscopic methods. The inhibitory activities of these isolates against five human cancer cell lines in vitro were also tested. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s13659-014-0007-5) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2014-03-18 /pmc/articles/PMC4004852/ /pubmed/24859375 http://dx.doi.org/10.1007/s13659-014-0007-5 Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ This article is published under license to BioMed Central Ltd. Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Original Article
Zhang, Jing-Jing
Yang, Xing-Wei
Ma, Jun-Zeng
Liu, Xia
Yang, Li-Xin
Yang, Sheng-Chao
Xu, Gang
Hypercohones D–G, New Polycyclic Polyprenylated Acylphloroglucinol Type Natural Products from Hypericum cohaerens
title Hypercohones D–G, New Polycyclic Polyprenylated Acylphloroglucinol Type Natural Products from Hypericum cohaerens
title_full Hypercohones D–G, New Polycyclic Polyprenylated Acylphloroglucinol Type Natural Products from Hypericum cohaerens
title_fullStr Hypercohones D–G, New Polycyclic Polyprenylated Acylphloroglucinol Type Natural Products from Hypericum cohaerens
title_full_unstemmed Hypercohones D–G, New Polycyclic Polyprenylated Acylphloroglucinol Type Natural Products from Hypericum cohaerens
title_short Hypercohones D–G, New Polycyclic Polyprenylated Acylphloroglucinol Type Natural Products from Hypericum cohaerens
title_sort hypercohones d–g, new polycyclic polyprenylated acylphloroglucinol type natural products from hypericum cohaerens
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004852/
https://www.ncbi.nlm.nih.gov/pubmed/24859375
http://dx.doi.org/10.1007/s13659-014-0007-5
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