Cargando…
Treatment of Iron-Loaded Veterinary Sarcoma by Artemisia annua
Artemisinin, a constituent of Artemisia annua L., is a well-known antimalarial drug. Artemisinin-type drugs also inhibit cancer growth in vitro and in vivo. Herbal extracts of A.annua inhibit the growth of cancer cell lines. Here, we report on the use of capsules containing powder of Herba Artemisia...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004853/ https://www.ncbi.nlm.nih.gov/pubmed/24859473 http://dx.doi.org/10.1007/s13659-014-0013-7 |
_version_ | 1782314020709072896 |
---|---|
author | Breuer, Elmar Efferth, Thomas |
author_facet | Breuer, Elmar Efferth, Thomas |
author_sort | Breuer, Elmar |
collection | PubMed |
description | Artemisinin, a constituent of Artemisia annua L., is a well-known antimalarial drug. Artemisinin-type drugs also inhibit cancer growth in vitro and in vivo. Herbal extracts of A.annua inhibit the growth of cancer cell lines. Here, we report on the use of capsules containing powder of Herba Artemisiae annuae to treat pet sarcoma. The surgical tumor removal as standard treatment was supplemented by adjuvant therapy with A.annua. One cat and one dog with fibrosarcoma survived 40 and 37 months, respectively, without tumor relapse. Two other dogs suffering from fibrosarcoma and hemangioendothelial sarcoma also showed complete remission and are still alive after 39 and 26 months, respectively. A.annua was well tolerated without noticeable side effects. These four cases indicate that A.annua may be a promising herbal drug for cancer therapy. |
format | Online Article Text |
id | pubmed-4004853 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-40048532014-05-07 Treatment of Iron-Loaded Veterinary Sarcoma by Artemisia annua Breuer, Elmar Efferth, Thomas Nat Prod Bioprospect Original Article Artemisinin, a constituent of Artemisia annua L., is a well-known antimalarial drug. Artemisinin-type drugs also inhibit cancer growth in vitro and in vivo. Herbal extracts of A.annua inhibit the growth of cancer cell lines. Here, we report on the use of capsules containing powder of Herba Artemisiae annuae to treat pet sarcoma. The surgical tumor removal as standard treatment was supplemented by adjuvant therapy with A.annua. One cat and one dog with fibrosarcoma survived 40 and 37 months, respectively, without tumor relapse. Two other dogs suffering from fibrosarcoma and hemangioendothelial sarcoma also showed complete remission and are still alive after 39 and 26 months, respectively. A.annua was well tolerated without noticeable side effects. These four cases indicate that A.annua may be a promising herbal drug for cancer therapy. Springer Berlin Heidelberg 2014-04-12 /pmc/articles/PMC4004853/ /pubmed/24859473 http://dx.doi.org/10.1007/s13659-014-0013-7 Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ This article is published under license to BioMed Central Ltd. Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
spellingShingle | Original Article Breuer, Elmar Efferth, Thomas Treatment of Iron-Loaded Veterinary Sarcoma by Artemisia annua |
title | Treatment of Iron-Loaded Veterinary Sarcoma by Artemisia annua |
title_full | Treatment of Iron-Loaded Veterinary Sarcoma by Artemisia annua |
title_fullStr | Treatment of Iron-Loaded Veterinary Sarcoma by Artemisia annua |
title_full_unstemmed | Treatment of Iron-Loaded Veterinary Sarcoma by Artemisia annua |
title_short | Treatment of Iron-Loaded Veterinary Sarcoma by Artemisia annua |
title_sort | treatment of iron-loaded veterinary sarcoma by artemisia annua |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004853/ https://www.ncbi.nlm.nih.gov/pubmed/24859473 http://dx.doi.org/10.1007/s13659-014-0013-7 |
work_keys_str_mv | AT breuerelmar treatmentofironloadedveterinarysarcomabyartemisiaannua AT efferththomas treatmentofironloadedveterinarysarcomabyartemisiaannua |