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Lead and Growth
Lead is highly toxic to the human body and children are much more vulnerable to lead toxicity than adults. Many studies have revealed that relatively low levels of blood lead can adversely affect human health, especially childhood growth and development. Blood lead levels (BLL) of children and adult...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society for Pediatric Endocrinology
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004863/ https://www.ncbi.nlm.nih.gov/pubmed/24790332 http://dx.doi.org/10.1297/cpe.15.123 |
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author | Kaji, Masayuki Nishi, Yoshikazu |
author_facet | Kaji, Masayuki Nishi, Yoshikazu |
author_sort | Kaji, Masayuki |
collection | PubMed |
description | Lead is highly toxic to the human body and children are much more vulnerable to lead toxicity than adults. Many studies have revealed that relatively low levels of blood lead can adversely affect human health, especially childhood growth and development. Blood lead levels (BLL) of children and adults have been decreasing recently almost all over the world, but a safety level for blood lead does not exist, and lead exposure is still a serious health problem especially for fetuses and children. Maternal lead burden causes fetal lead exposure and increases the risk of abortions, prematurity, low birth weight, and some minor anomalies. Infant BLL are inversely associated with weight gain. A negative relationship between somatic growth and BLL in children has been revealed. It has been suggested that lead exposure causes decrease of gonadotropin secretion of adolescents and delay of pubertal development. Several studies have revealed that children who are exposed to cigarette smoke have higher BLL than children who are not. Children should be protected from cigarette smoke for the purpose of avoiding the risk of increased BLL which might adversely affect their intellectual development and physical growth. |
format | Online Article Text |
id | pubmed-4004863 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | The Japanese Society for Pediatric Endocrinology |
record_format | MEDLINE/PubMed |
spelling | pubmed-40048632014-04-30 Lead and Growth Kaji, Masayuki Nishi, Yoshikazu Clin Pediatr Endocrinol Review Article Lead is highly toxic to the human body and children are much more vulnerable to lead toxicity than adults. Many studies have revealed that relatively low levels of blood lead can adversely affect human health, especially childhood growth and development. Blood lead levels (BLL) of children and adults have been decreasing recently almost all over the world, but a safety level for blood lead does not exist, and lead exposure is still a serious health problem especially for fetuses and children. Maternal lead burden causes fetal lead exposure and increases the risk of abortions, prematurity, low birth weight, and some minor anomalies. Infant BLL are inversely associated with weight gain. A negative relationship between somatic growth and BLL in children has been revealed. It has been suggested that lead exposure causes decrease of gonadotropin secretion of adolescents and delay of pubertal development. Several studies have revealed that children who are exposed to cigarette smoke have higher BLL than children who are not. Children should be protected from cigarette smoke for the purpose of avoiding the risk of increased BLL which might adversely affect their intellectual development and physical growth. The Japanese Society for Pediatric Endocrinology 2006-11-03 2006 /pmc/articles/PMC4004863/ /pubmed/24790332 http://dx.doi.org/10.1297/cpe.15.123 Text en 2006©The Japanese Society for Pediatric Endocrinology http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. |
spellingShingle | Review Article Kaji, Masayuki Nishi, Yoshikazu Lead and Growth |
title | Lead and Growth |
title_full | Lead and Growth |
title_fullStr | Lead and Growth |
title_full_unstemmed | Lead and Growth |
title_short | Lead and Growth |
title_sort | lead and growth |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004863/ https://www.ncbi.nlm.nih.gov/pubmed/24790332 http://dx.doi.org/10.1297/cpe.15.123 |
work_keys_str_mv | AT kajimasayuki leadandgrowth AT nishiyoshikazu leadandgrowth |