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Diacylglycerol kinase as a possible therapeutic target for neuronal diseases
Diacylglycerol kinase (DGK) is a lipid kinase converting diacylglycerol to phosphatidic acid, and regulates many enzymes including protein kinase C, phosphatidylinositol 4-phosphate 5-kinase, and mTOR. To date, ten mammalian DGK subtypes have been cloned and divided into five groups, and they show s...
Autores principales: | Shirai, Yasuhito, Saito, Naoaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005014/ https://www.ncbi.nlm.nih.gov/pubmed/24708409 http://dx.doi.org/10.1186/1423-0127-21-28 |
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