A single-nucleotide polymorphism in the human p27(kip1 )gene (-838C>A) affects basal promoter activity and the risk of myocardial infarction

BACKGROUND: Excessive proliferation of vascular smooth muscle cells and leukocytes within the artery wall is a major event in the development of atherosclerosis. The growth suppressor p27(kip1 )associates with several cyclin-dependent kinase/cyclin complexes, thereby abrogating their capacity to ind...

Descripción completa

Detalles Bibliográficos
Autores principales: González, Pelayo, Díez-Juan, Antonio, Coto, Eliecer, Álvarez, Victoria, Reguero, Julian R, Batalla, Alberto, Andrés, Vicente
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC400507/
https://www.ncbi.nlm.nih.gov/pubmed/15061869
http://dx.doi.org/10.1186/1741-7007-2-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC400507/
https://www.ncbi.nlm.nih.gov/pubmed/15061869
http://dx.doi.org/10.1186/1741-7007-2-5

Ejemplares similares