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A single-nucleotide polymorphism in the human p27(kip1 )gene (-838C>A) affects basal promoter activity and the risk of myocardial infarction
BACKGROUND: Excessive proliferation of vascular smooth muscle cells and leukocytes within the artery wall is a major event in the development of atherosclerosis. The growth suppressor p27(kip1 )associates with several cyclin-dependent kinase/cyclin complexes, thereby abrogating their capacity to ind...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC400507/ https://www.ncbi.nlm.nih.gov/pubmed/15061869 http://dx.doi.org/10.1186/1741-7007-2-5 |