Cargando…

IL-4 receptor alpha single-nucleotide polymorphisms rs1805010 and rs1801275 are associated with increased risk of asthma in a Saudi Arabian population

BACKGROUND: The IL-4 receptor alpha subunit (IL-4Rα), when associated with the common gamma chain receptor, or the IL-13Rα1 subunit, transduces signals to STAT6 in response to IL-4 and IL-13 stimulations. This results in a number of cell-specific responses including Th2 differentiation, lymphocyte p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Al-Muhsen, Saleh, Vazquez-Tello, Alejandro, Alzaabi, Ashraf, Al-Hajjaj, Mohamed S., Al-Jahdali, Hamdan H., Halwani, Rabih
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005166/ https://www.ncbi.nlm.nih.gov/pubmed/24791170 http://dx.doi.org/10.4103/1817-1737.128849

Ejemplares similares

T1 and T2 ADAM33 single nucleotide polymorphisms and the risk of childhood asthma in a Saudi Arabian population: a pilot study
por: Al-Khayyat, Arwa Ishaq, et al.
Publicado: (2012)

Mechanisims of asthma and allergic disease – 1090. Eosinophils enhance airway smooth muscle cell proliferation via the release of cystl leukotrines
por: Al Muhsen, Saleh, et al.
Publicado: (2013)

Mechanisims of asthma and allergic disease – 1092. Regulation of profibrotic cytokines release from human eosinophils by Th17 cytokines
por: Halwani, Rabih, et al.
Publicado: (2013)

Th17 cytokines regulate profibrotic cytokines release by human eosinophils
por: Halwani, Rabih, et al.
Publicado: (2012)

127 Eosinophils Enhance Airway Smooth Muscle Cell Proliferation Via the Release of Cysteinyl Leukotrines
por: Halwani, Rabih, et al.
Publicado: (2012)

Poor asthma education and medication compliance are associated with increased emergency department visits by asthmatic children
por: Al-Muhsen, Saleh, et al.
Publicado: (2015)

Eosinophilic pneumonia: experience at two tertiary care referral hospitals in Saudi Arabia
por: Al-Jahdali, Hamdan, et al.
Publicado: (2012)

514 Role of TH-17 Cytokines in Steroid Insensitivity in Peripheral Blood Mononuclear Cells. Relationship to GR-alpha and GR-beta Expression
por: Vazquez-Tello, Alejandro, et al.
Publicado: (2012)

Th17 cytokines induce pro-fibrotic cytokines release from human eosinophils
por: Al-Muhsen, Saleh, et al.
Publicado: (2013)

Factors associated with patient visits to the emergency department for asthma therapy
por: AL-Jahdali, Hamdan, et al.
Publicado: (2012)

Protective Association of Single Nucleotide Polymorphisms rs1861868-FTO and rs7975232-VDR and Obesity in Saudi Females
por: Al Asoom, Lubna Ibrahim, et al.
Publicado: (2020)

IL-17 Enhances Chemotaxis of Primary Human B Cells during Asthma
por: Halwani, Rabih, et al.
Publicado: (2014)

Improper inhaler technique is associated with poor asthma control and frequent emergency department visits
por: AL-Jahdali, Hamdan, et al.
Publicado: (2013)

Clinical characteristics, risk factors, and rate of severity of a nationwide COVID-19 Saudi cohort
por: Al-Numair, Nouf S., et al.
Publicado: (2022)

513 IL-17 Role in the Regulatory Function of B Cells
por: Vazquez-Tello, Alejandro, et al.
Publicado: (2012)

Rs10204525 Polymorphism of the Programmed Death (PD-1) Gene Is Associated with Increased Risk in a Saudi Arabian Population with Colorectal Cancer
por: Al-Harbi, Nouf, et al.
Publicado: (2022)

Editorial: Dysregulation of immunity predisposing to severe COVID-19 infection
por: Halwani, Rabih, et al.
Publicado: (2022)

Th-17 regulatory cytokines inhibit corticosteroid induced airway structural cells apoptosis
por: Halwani, Rabih, et al.
Publicado: (2016)

Psychological symptoms in adult Saudi Arabian cancer patients: prevalence and association with self-rated oral health
por: Ahmed, Anwar E, et al.
Publicado: (2018)

Association of Vitamin D Receptor Gene Polymorphisms with Colorectal Cancer in a Saudi Arabian Population
por: Alkhayal, Khayal A., et al.
Publicado: (2016)

Improving risk prediction for pancreatic cancer in symptomatic patients: a Saudi Arabian study
por: Ahmed, Anwar E, et al.
Publicado: (2018)

Modeling risk assessment for breast cancer in symptomatic women: a Saudi Arabian study
por: Ahmed, Anwar E, et al.
Publicado: (2019)

Seventy-two-hour emergency department revisits among adults with chronic diseases: a Saudi Arabian study
por: Ahmed, Anwar E, et al.
Publicado: (2018)

No genetic relationship between TLR2 rs4696480, rs3804100, and rs3804099 gene polymorphisms and female breast cancer in Saudi populations
por: Semlali, Abdelhabib, et al.
Publicado: (2017)

Emergency department 72-hour revisits among children with chronic diseases: a Saudi Arabian study
por: Ahmed, Anwar E., et al.
Publicado: (2018)

Association between Hepatitis C Virus Viremia and the rs12979860, rs2228145 and rs1800795 SNP (CT/AC/GG) Genotype in Saudi Kidney Transplant Recipients
por: Alkharsah, Khaled R., et al.
Publicado: (2020)

Distribution of selected gene polymorphisms of UGT1A1 in a Saudi population
por: Alkharfy, Khalid M., et al.
Publicado: (2013)

Saudi Arabian retinopathy of prematurity national telemedicine program: Achievements and challenges
por: Al Amro, Saleh A., et al.
Publicado: (2022)

Association of two single nucleotide polymorphisms rs10407022 and rs3741664 with the risk of primary ovarian insufficiency in a sample of Iraqi women
por: Rafaa, Tamadher Abbas, et al.
Publicado: (2020)

Safety and pharmacokinetics of extended use of palivizumab in Saudi Arabian infants and children
por: al-Alaiyan, Saleh, et al.
Publicado: (2015)

Sequence Analysis of APOA5 Among the Kuwaiti Population Identifies Association of rs2072560, rs2266788, and rs662799 With TG and VLDL Levels
por: Jasim, Anfal A., et al.
Publicado: (2018)

Saudi guidelines for testing and treatment of latent tuberculosis infection
por: Al Jahdali, Hamdan H., et al.
Publicado: (2010)

Botanical candidates from Saudi Arabian flora as potential therapeutics for Plasmodium infection
por: Al-Quraishy, Saleh, et al.
Publicado: (2021)

Exome sequencing of Saudi Arabian patients with ADPKD
por: Al-Muhanna, Fahad A., et al.
Publicado: (2019)

The prevalence of restless leg syndrome among pregnant Saudi women
por: Khan, Mohmd, et al.
Publicado: (2018)

Obesity in the Balinese is associated with FTO rs9939609 and rs1421085 single nucleotide polymorphisms
por: Priliani, Lidwina, et al.
Publicado: (2020)

Attitude of Saudi Arabian adults towards consanguineous marriage
por: Alharbi, Omar A., et al.
Publicado: (2015)

Favipiravir Effectiveness and Safety in Hospitalized Moderate-Severe COVID-19 Patients: Observational Prospective Multicenter Investigation in Saudi Arabia
por: Al-Muhsen, Saleh, et al.
Publicado: (2022)

Shared clinical decision making: A Saudi Arabian perspective
por: AlHaqwi, Ali I., et al.
Publicado: (2015)

Prevalence of UDP-glucuronosyltransferase polymorphisms (UGT1A6∗2, 1A7∗12, 1A8∗3, 1A9∗3, 2B7∗2, and 2B15∗2) in a Saudi population
por: Alkharfy, Khalid M., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_akjdccdfjj7n19kl4f7l40bs1f