Influence of βS-globin haplotypes hydroxyurea on tumor necrosis factor-alpha levels in sickle cell anemia

BACKGROUND: Sickle cell anemia is a chronic inflammatory disease characterized by an increased production of proinflammatory cytokines including tumor necrosis factor-alpha. Hydroxyurea, by decreasing the polymerization of hemoglobin, reduces inflammatory states. The effect of the genetic polymorphi...

Descripción completa

Detalles Bibliográficos
Autores principales: Laurentino, Marília Rocha, Filho, Pedro Aurio Maia, Barbosa, Maritza Cavalcante, Bandeira, Izabel Cristina Justino, da Silva Rocha, Lilianne Brito, Gonçalves, Romelia Pinheiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Hematologia e Hemoterapia 2014
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005510/
https://www.ncbi.nlm.nih.gov/pubmed/24790537
http://dx.doi.org/10.5581/1516-8484.20140028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005510/
https://www.ncbi.nlm.nih.gov/pubmed/24790537
http://dx.doi.org/10.5581/1516-8484.20140028

Ejemplares similares