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Glutamine attenuates the inhibitory effect of methotrexate on TLR signaling during intestinal chemotherapy-induced mucositis in a rat

Toll-like receptor 4 (TLR-4) is crucial in maintaining intestinal epithelial homeostasis, participates in a vigorous signaling process and heightens inflammatory cytokine output. The objective of this study was to determine the effects of glutamine (GLN) on TLR-4 signaling in intestinal mucosa durin...

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Detalles Bibliográficos
Autores principales:	Sukhotnik, Igor, Pollak, Yulia, Coran, Arnold G, Pilatov, Janna, Bejar, Jacob, Mogilner, Jorge G, Berkowitz, Drora
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005622/ https://www.ncbi.nlm.nih.gov/pubmed/24742067 http://dx.doi.org/10.1186/1743-7075-11-17

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