Domain movements of the enhancer-dependent sigma factor drive DNA delivery into the RNA polymerase active site: insights from single molecule studies

Recognition of bacterial promoters is regulated by two distinct classes of sequence-specific sigma factors, σ(70) or σ(54), that differ both in their primary sequence and in the requirement of the latter for activation via enhancer-bound upstream activators. The σ(54) version controls gene expressio...

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Detalles Bibliográficos
Autores principales: Sharma, Amit, Leach, Robert N., Gell, Christopher, Zhang, Nan, Burrows, Patricia C., Shepherd, Dale A., Wigneshweraraj, Sivaramesh, Smith, David Alastair, Zhang, Xiaodong, Buck, Martin, Stockley, Peter G., Tuma, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005640/
https://www.ncbi.nlm.nih.gov/pubmed/24553251
http://dx.doi.org/10.1093/nar/gku146

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