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ARTD2 activity is stimulated by RNA

ADP-ribosyltransferases (ARTs) are important enzymes that regulate the genotoxic stress response and the maintenance of genome integrity. ARTD1 (PARP1) and ARTD2 (PARP2) are homologous proteins that modify themselves and target proteins by the addition of mono- and poly-ADP-ribose (PAR) moieties. Bo...

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Detalles Bibliográficos
Autores principales: Léger, Karolin, Bär, Dominik, Savić, Nataša, Santoro, Raffaella, Hottiger, Michael O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005644/
https://www.ncbi.nlm.nih.gov/pubmed/24510188
http://dx.doi.org/10.1093/nar/gku131