Novel functional small RNAs are selectively loaded onto mammalian Ago1

Argonaute (Ago) proteins function in RNA silencing as components of the RNA-induced silencing complex (RISC). In lower organisms, the small interfering RNA and miRNA pathways diverge due in part to sorting mechanisms that direct distinct small RNA (sRNA) duplexes onto specific Ago-RISCs. However, su...

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Detalles Bibliográficos
Autores principales: Yamakawa, Natsuko, Okuyama, Kazuki, Ogata, Jun, Kanai, Akinori, Helwak, Aleksandra, Takamatsu, Masako, Imadome, Ken-ichi, Takakura, Kohei, Chanda, Bidisha, Kurosaki, Natsumi, Yamamoto, Haruna, Ando, Kiyoshi, Matsui, Hirotaka, Inaba, Toshiya, Kotani, Ai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005649/
https://www.ncbi.nlm.nih.gov/pubmed/24627180
http://dx.doi.org/10.1093/nar/gku137

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