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Bimodal high-affinity association of Brd4 with murine leukemia virus integrase and mononucleosomes

The importance of understanding the molecular mechanisms of murine leukemia virus (MLV) integration into host chromatin is highlighted by the development of MLV-based vectors for human gene-therapy. We have recently identified BET proteins (Brd2, 3 and 4) as the main cellular binding partners of MLV...

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Detalles Bibliográficos
Autores principales:	Larue, Ross C., Plumb, Matthew R., Crowe, Brandon L., Shkriabai, Nikoloz, Sharma, Amit, DiFiore, Julia, Malani, Nirav, Aiyer, Sriram S., Roth, Monica J., Bushman, Frederic D., Foster, Mark P., Kvaratskhelia, Mamuka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005663/ https://www.ncbi.nlm.nih.gov/pubmed/24520112 http://dx.doi.org/10.1093/nar/gku135

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