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In vitro assembly and activity of an archaeal CRISPR-Cas type I-A Cascade interference complex

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-CRISPR-associated (Cas) systems of type I use a Cas ribonucleoprotein complex for antiviral defense (Cascade) to mediate the targeting and degradation of foreign DNA. To address molecular features of the archaeal type I-A Cascade int...

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Detalles Bibliográficos
Autores principales:	Plagens, André, Tripp, Vanessa, Daume, Michael, Sharma, Kundan, Klingl, Andreas, Hrle, Ajla, Conti, Elena, Urlaub, Henning, Randau, Lennart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005679/ https://www.ncbi.nlm.nih.gov/pubmed/24500198 http://dx.doi.org/10.1093/nar/gku120

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