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Innate lymphoid cells integrate stromal and immune signals to enhance antibody production by splenic marginal zone B cells
Innate lymphoid cells (ILCs) regulate stromal, epithelial and immune cells, but their impact on B cells remains unclear. We identified RORγt(+) ILCs nearby the marginal zone (MZ), a splenic compartment containing innate-like B cells that respond to circulating T cell-independent (TI) antigens. Speni...
Autores principales: | Magri, Giuliana, Miyajima, Michio, Bascones, Sabrina, Mortha, Arthur, Puga, Irene, Cassis, Linda, Barra, Carolina M., Comerma, Laura, Chudnovskiy, Aleksey, Gentile, Maurizio, Llige, David, Cols, Montserrat, Serrano, Sergi, Aróstegui, Juan Ignacio, Juan, Manel, Yagüe, Jordi, Merad, Miriam, Fagarasan, Sidonia, Cerutti, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005806/ https://www.ncbi.nlm.nih.gov/pubmed/24562309 http://dx.doi.org/10.1038/ni.2830 |
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