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Streptozotocin-induced diabetes prolongs twitch duration without affecting the energetics of isolated ventricular trabeculae

BACKGROUND: Diabetes induces numerous electrical, ionic and biochemical defects in the heart. A general feature of diabetic myocardium is its low rate of activity, commonly characterised by prolonged twitch duration. This diabetes-induced mechanical change, however, seems to have no effect on contra...

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Detalles Bibliográficos
Autores principales:	Han, June-Chiew, Tran, Kenneth, Nielsen, Poul MF, Taberner, Andrew J, Loiselle, Denis S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005834/ https://www.ncbi.nlm.nih.gov/pubmed/24731754 http://dx.doi.org/10.1186/1475-2840-13-79

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