Cargando…

Prevalence of Shigella, Salmonella and Cmpylobacter Species and Their Susceptibility Patters Among Under Five Children With Diarrhea in Hawassa Town, South Ethiopia

BACKGROUND: Diarrhea is the leading cause of morbidity and mortality in under-five children in developing countries including Ethiopia. Therefore, up-to-date data on etiologic agent and susceptibility pattern are important for the management of bacterial diarrhea in under-five children, which was th...

Descripción completa

Detalles Bibliográficos
Autores principales: Mulatu, Getamesay, Beyene, Getenet, Zeynudin, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research and Publications Office of Jimma University 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006203/
https://www.ncbi.nlm.nih.gov/pubmed/24795510
_version_ 1782314200176001024
author Mulatu, Getamesay
Beyene, Getenet
Zeynudin, Ahmed
author_facet Mulatu, Getamesay
Beyene, Getenet
Zeynudin, Ahmed
author_sort Mulatu, Getamesay
collection PubMed
description BACKGROUND: Diarrhea is the leading cause of morbidity and mortality in under-five children in developing countries including Ethiopia. Therefore, up-to-date data on etiologic agent and susceptibility pattern are important for the management of bacterial diarrhea in under-five children, which was the main objective of this study. METHOD: A cross-sectional study was conducted at Hawassa Adare Hospital and Millennium Health Center from June 6 to October 28, 2011. A total of 158 under-five children with diarrhea were selected using convenient sampling technique. Demographic and clinical data were collected using questionnaire. Fecal samples were collected and processed for bacterial isolation, and antimicrobial susceptibility testing following standard bacteriological techniques. RESULT: A total of 158 fecal samples were collected from 81(51.3%) males and 77(48.7%) females of under-five children with diarrhea. Of the 158 fecal samples, 35(22.2%) bacterial pathogens were isolated. The isolated bacteria were Campylobacter species, 20 (12.7%), Shigella species, 11 (7.0%), and Salmonella species, 4 (2.5%). The majority of the isolates were sensitive to Chloramphenicol, Ciprofloxacin, Nalidixic acid and Cotrimoxazol and high rate of drug resistance was observed against Erythromycin and Amoxicillin. CONCLUSIONS: The finding of this study indicates that Campylobacter species were the predominant etiologies and the presence of bacterial isolates resistant to the commonly prescribed drugs for treating diarrhea in children. Therefore, periodic monitoring of etiologic agent with their drug resistant pattern is essential in the management of diarrhea in children.
format Online
Article
Text
id pubmed-4006203
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Research and Publications Office of Jimma University
record_format MEDLINE/PubMed
spelling pubmed-40062032014-05-02 Prevalence of Shigella, Salmonella and Cmpylobacter Species and Their Susceptibility Patters Among Under Five Children With Diarrhea in Hawassa Town, South Ethiopia Mulatu, Getamesay Beyene, Getenet Zeynudin, Ahmed Ethiop J Health Sci Original Article BACKGROUND: Diarrhea is the leading cause of morbidity and mortality in under-five children in developing countries including Ethiopia. Therefore, up-to-date data on etiologic agent and susceptibility pattern are important for the management of bacterial diarrhea in under-five children, which was the main objective of this study. METHOD: A cross-sectional study was conducted at Hawassa Adare Hospital and Millennium Health Center from June 6 to October 28, 2011. A total of 158 under-five children with diarrhea were selected using convenient sampling technique. Demographic and clinical data were collected using questionnaire. Fecal samples were collected and processed for bacterial isolation, and antimicrobial susceptibility testing following standard bacteriological techniques. RESULT: A total of 158 fecal samples were collected from 81(51.3%) males and 77(48.7%) females of under-five children with diarrhea. Of the 158 fecal samples, 35(22.2%) bacterial pathogens were isolated. The isolated bacteria were Campylobacter species, 20 (12.7%), Shigella species, 11 (7.0%), and Salmonella species, 4 (2.5%). The majority of the isolates were sensitive to Chloramphenicol, Ciprofloxacin, Nalidixic acid and Cotrimoxazol and high rate of drug resistance was observed against Erythromycin and Amoxicillin. CONCLUSIONS: The finding of this study indicates that Campylobacter species were the predominant etiologies and the presence of bacterial isolates resistant to the commonly prescribed drugs for treating diarrhea in children. Therefore, periodic monitoring of etiologic agent with their drug resistant pattern is essential in the management of diarrhea in children. Research and Publications Office of Jimma University 2014-04 /pmc/articles/PMC4006203/ /pubmed/24795510 Text en Copyright © Jimma University, Research & Publications Office 2014
spellingShingle Original Article
Mulatu, Getamesay
Beyene, Getenet
Zeynudin, Ahmed
Prevalence of Shigella, Salmonella and Cmpylobacter Species and Their Susceptibility Patters Among Under Five Children With Diarrhea in Hawassa Town, South Ethiopia
title Prevalence of Shigella, Salmonella and Cmpylobacter Species and Their Susceptibility Patters Among Under Five Children With Diarrhea in Hawassa Town, South Ethiopia
title_full Prevalence of Shigella, Salmonella and Cmpylobacter Species and Their Susceptibility Patters Among Under Five Children With Diarrhea in Hawassa Town, South Ethiopia
title_fullStr Prevalence of Shigella, Salmonella and Cmpylobacter Species and Their Susceptibility Patters Among Under Five Children With Diarrhea in Hawassa Town, South Ethiopia
title_full_unstemmed Prevalence of Shigella, Salmonella and Cmpylobacter Species and Their Susceptibility Patters Among Under Five Children With Diarrhea in Hawassa Town, South Ethiopia
title_short Prevalence of Shigella, Salmonella and Cmpylobacter Species and Their Susceptibility Patters Among Under Five Children With Diarrhea in Hawassa Town, South Ethiopia
title_sort prevalence of shigella, salmonella and cmpylobacter species and their susceptibility patters among under five children with diarrhea in hawassa town, south ethiopia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006203/
https://www.ncbi.nlm.nih.gov/pubmed/24795510
work_keys_str_mv AT mulatugetamesay prevalenceofshigellasalmonellaandcmpylobacterspeciesandtheirsusceptibilitypattersamongunderfivechildrenwithdiarrheainhawassatownsouthethiopia
AT beyenegetenet prevalenceofshigellasalmonellaandcmpylobacterspeciesandtheirsusceptibilitypattersamongunderfivechildrenwithdiarrheainhawassatownsouthethiopia
AT zeynudinahmed prevalenceofshigellasalmonellaandcmpylobacterspeciesandtheirsusceptibilitypattersamongunderfivechildrenwithdiarrheainhawassatownsouthethiopia