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Behavioural and Psychological Symptoms in Poststroke Vascular Cognitive Impairment
Background. Behavioural and psychological symptoms of dementia (BPSD) cause significant patient and caregiver morbidity in vascular cognitive impairment (VCI). Objectives. To study and compare the occurrence and severity of BPSD between multi-infarct dementia (MID), subcortical ischaemic vascular di...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006603/ https://www.ncbi.nlm.nih.gov/pubmed/24825957 http://dx.doi.org/10.1155/2014/430128 |
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author | Gupta, Meena Dasgupta, Abhijit Khwaja, Geeta Anjum Chowdhury, Debashish Patidar, Yogesh Batra, Amit |
author_facet | Gupta, Meena Dasgupta, Abhijit Khwaja, Geeta Anjum Chowdhury, Debashish Patidar, Yogesh Batra, Amit |
author_sort | Gupta, Meena |
collection | PubMed |
description | Background. Behavioural and psychological symptoms of dementia (BPSD) cause significant patient and caregiver morbidity in vascular cognitive impairment (VCI). Objectives. To study and compare the occurrence and severity of BPSD between multi-infarct dementia (MID), subcortical ischaemic vascular disease (SIVD), and strategic infarct subtypes of poststroke VCI and to evaluate the relationship of these symptoms with the severity of cognitive impairment. Methods. Sixty patients with poststroke VCI were classified into MID, SIVD, and strategic infarct subtypes. BPSD were studied by the neuropsychiatric inventory (NPI). The severity of cognitive impairment was evaluated by the clinical dementia rating scale (CDR). Results. 95% of cases had at least one neuropsychiatric symptom, with depression being the commonest, irrespective of subtype or severity of VCI. Strategic infarct patients had the lowest frequency of all symptoms. SIVD showed a higher frequency and severity of apathy and higher total NPI scores, compared to MID. Apathy and appetite disturbances occurred more commonly with increasing CDR scores. The total NPI score correlated positively with the CDR score. Conclusion. Depression was the commonest neuropsychiatric symptom in VCI. The neuropsychiatric profiles of MID and SIVD were similar. The frequency and severity of apathy and the net burden of BPSD increased with increasing cognitive impairment. |
format | Online Article Text |
id | pubmed-4006603 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-40066032014-05-13 Behavioural and Psychological Symptoms in Poststroke Vascular Cognitive Impairment Gupta, Meena Dasgupta, Abhijit Khwaja, Geeta Anjum Chowdhury, Debashish Patidar, Yogesh Batra, Amit Behav Neurol Research Article Background. Behavioural and psychological symptoms of dementia (BPSD) cause significant patient and caregiver morbidity in vascular cognitive impairment (VCI). Objectives. To study and compare the occurrence and severity of BPSD between multi-infarct dementia (MID), subcortical ischaemic vascular disease (SIVD), and strategic infarct subtypes of poststroke VCI and to evaluate the relationship of these symptoms with the severity of cognitive impairment. Methods. Sixty patients with poststroke VCI were classified into MID, SIVD, and strategic infarct subtypes. BPSD were studied by the neuropsychiatric inventory (NPI). The severity of cognitive impairment was evaluated by the clinical dementia rating scale (CDR). Results. 95% of cases had at least one neuropsychiatric symptom, with depression being the commonest, irrespective of subtype or severity of VCI. Strategic infarct patients had the lowest frequency of all symptoms. SIVD showed a higher frequency and severity of apathy and higher total NPI scores, compared to MID. Apathy and appetite disturbances occurred more commonly with increasing CDR scores. The total NPI score correlated positively with the CDR score. Conclusion. Depression was the commonest neuropsychiatric symptom in VCI. The neuropsychiatric profiles of MID and SIVD were similar. The frequency and severity of apathy and the net burden of BPSD increased with increasing cognitive impairment. Hindawi Publishing Corporation 2014 2014-03-02 /pmc/articles/PMC4006603/ /pubmed/24825957 http://dx.doi.org/10.1155/2014/430128 Text en Copyright © 2014 Meena Gupta et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Gupta, Meena Dasgupta, Abhijit Khwaja, Geeta Anjum Chowdhury, Debashish Patidar, Yogesh Batra, Amit Behavioural and Psychological Symptoms in Poststroke Vascular Cognitive Impairment |
title | Behavioural and Psychological Symptoms in Poststroke Vascular Cognitive Impairment |
title_full | Behavioural and Psychological Symptoms in Poststroke Vascular Cognitive Impairment |
title_fullStr | Behavioural and Psychological Symptoms in Poststroke Vascular Cognitive Impairment |
title_full_unstemmed | Behavioural and Psychological Symptoms in Poststroke Vascular Cognitive Impairment |
title_short | Behavioural and Psychological Symptoms in Poststroke Vascular Cognitive Impairment |
title_sort | behavioural and psychological symptoms in poststroke vascular cognitive impairment |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006603/ https://www.ncbi.nlm.nih.gov/pubmed/24825957 http://dx.doi.org/10.1155/2014/430128 |
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