Drosophila melanogaster Hox Transcription Factors Access the RNA Polymerase II Machinery through Direct Homeodomain Binding to a Conserved Motif of Mediator Subunit Med19

Hox genes in species across the metazoa encode transcription factors (TFs) containing highly-conserved homeodomains that bind target DNA sequences to regulate batteries of developmental target genes. DNA-bound Hox proteins, together with other TF partners, induce an appropriate transcriptional respo...

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Detalles Bibliográficos
Autores principales: Boube, Muriel, Hudry, Bruno, Immarigeon, Clément, Carrier, Yannick, Bernat-Fabre, Sandra, Merabet, Samir, Graba, Yacine, Bourbon, Henri-Marc, Cribbs, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006704/
https://www.ncbi.nlm.nih.gov/pubmed/24786462
http://dx.doi.org/10.1371/journal.pgen.1004303

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