Copy Number Variation Is a Fundamental Aspect of the Placental Genome

Discovery of lineage-specific somatic copy number variation (CNV) in mammals has led to debate over whether CNVs are mutations that propagate disease or whether they are a normal, and even essential, aspect of cell biology. We show that 1,000N polyploid trophoblast giant cells (TGCs) of the mouse pl...

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Detalles Bibliográficos
Autores principales: Hannibal, Roberta L., Chuong, Edward B., Rivera-Mulia, Juan Carlos, Gilbert, David M., Valouev, Anton, Baker, Julie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006706/
https://www.ncbi.nlm.nih.gov/pubmed/24785991
http://dx.doi.org/10.1371/journal.pgen.1004290

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