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Single Nucleotide Variants in Transcription Factors Associate More Tightly with Phenotype than with Gene Expression
Mapping the polymorphisms responsible for variation in gene expression, known as Expression Quantitative Trait Loci (eQTL), is a common strategy for investigating the molecular basis of disease. Despite numerous eQTL studies, the relationship between the explanatory power of variants on gene express...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006743/ https://www.ncbi.nlm.nih.gov/pubmed/24784239 http://dx.doi.org/10.1371/journal.pgen.1004325 |