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Efficacy of a Metalloproteinase Inhibitor in Spinal Cord Injured Dogs
Matrix metalloproteinase-9 is elevated within the acutely injured murine spinal cord and blockade of this early proteolytic activity with GM6001, a broad-spectrum matrix metalloproteinase inhibitor, results in improved recovery after spinal cord injury. As matrix metalloproteinase-9 is likewise acut...
Autores principales: | Levine, Jonathan M., Cohen, Noah D., Heller, Michael, Fajt, Virginia R., Levine, Gwendolyn J., Kerwin, Sharon C., Trivedi, Alpa A., Fandel, Thomas M., Werb, Zena, Modestino, Augusta, Noble-Haeusslein, Linda J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006832/ https://www.ncbi.nlm.nih.gov/pubmed/24788791 http://dx.doi.org/10.1371/journal.pone.0096408 |
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