The immune landscape of human tumors: Implications for cancer immunotherapy

Understanding the spontaneous immune response of cancer patients is critical for the design of efficient anticancer immunotherapies. The power of integrative tumor immunology approaches allowed for a comprehensive view of the immune system evolution in the course of tumor progression and recurrence....

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Detalles Bibliográficos
Autores principales: Bindea, Gabriela, Mlecnik, Bernhard, Angell, Helen K, Galon, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006852/
https://www.ncbi.nlm.nih.gov/pubmed/24800163
http://dx.doi.org/10.4161/onci.27456
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author Bindea, Gabriela
Mlecnik, Bernhard
Angell, Helen K
Galon, Jérôme
author_facet Bindea, Gabriela
Mlecnik, Bernhard
Angell, Helen K
Galon, Jérôme
author_sort Bindea, Gabriela
collection PubMed
description Understanding the spontaneous immune response of cancer patients is critical for the design of efficient anticancer immunotherapies. The power of integrative tumor immunology approaches allowed for a comprehensive view of the immune system evolution in the course of tumor progression and recurrence. We have demonstrated that tumor-infiltrating immune cells are spatiotemporally regulated, a finding that has profound implications for the development of efficient anticancer immunotherapies.
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spelling pubmed-40068522014-05-05 The immune landscape of human tumors: Implications for cancer immunotherapy Bindea, Gabriela Mlecnik, Bernhard Angell, Helen K Galon, Jérôme Oncoimmunology Author's View Understanding the spontaneous immune response of cancer patients is critical for the design of efficient anticancer immunotherapies. The power of integrative tumor immunology approaches allowed for a comprehensive view of the immune system evolution in the course of tumor progression and recurrence. We have demonstrated that tumor-infiltrating immune cells are spatiotemporally regulated, a finding that has profound implications for the development of efficient anticancer immunotherapies. Landes Bioscience 2014-01-03 /pmc/articles/PMC4006852/ /pubmed/24800163 http://dx.doi.org/10.4161/onci.27456 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Bindea, Gabriela
Mlecnik, Bernhard
Angell, Helen K
Galon, Jérôme
The immune landscape of human tumors: Implications for cancer immunotherapy
title The immune landscape of human tumors: Implications for cancer immunotherapy
title_full The immune landscape of human tumors: Implications for cancer immunotherapy
title_fullStr The immune landscape of human tumors: Implications for cancer immunotherapy
title_full_unstemmed The immune landscape of human tumors: Implications for cancer immunotherapy
title_short The immune landscape of human tumors: Implications for cancer immunotherapy
title_sort immune landscape of human tumors: implications for cancer immunotherapy
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006852/
https://www.ncbi.nlm.nih.gov/pubmed/24800163
http://dx.doi.org/10.4161/onci.27456
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