A Role for LHC1 in Higher Order Structure and Complement Binding of the Cryptococcus neoformans Capsule

Polysaccharide capsules are important virulence factors for many microbial pathogens including the opportunistic fungus Cryptococcus neoformans. In the present study, we demonstrate an unusual role for a secreted lactonohydrolase of C. neoformans, LHC1 in capsular higher order structure. Analysis of...

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Detalles Bibliográficos
Autores principales: Park, Yoon-Dong, Shin, Soowan, Panepinto, John, Ramos, Jeanie, Qiu, Jin, Frases, Susana, Albuquerque, Patricia, Cordero, Radames J. B., Zhang, Nannan, Himmelreich, Uwe, Beenhouwer, David, Bennett, John E., Casadevall, Arturo, Williamson, Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006888/
https://www.ncbi.nlm.nih.gov/pubmed/24789368
http://dx.doi.org/10.1371/journal.ppat.1004037

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