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Chaperonin CCT-Mediated AIB1 Folding Promotes the Growth of ERα-Positive Breast Cancer Cells on Hard Substrates

Clinical observations have revealed a strong association between estrogen receptor alpha (ERα)-positive tumors and the development of bone metastases, however, the mechanism underlying this association remains unknown. We cultured MCF-7 (ERα-positive) on different rigidity substrates. Compared with...

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Detalles Bibliográficos
Autores principales: Chen, Li, Zhang, Ze, Qiu, Juhui, Zhang, Lingling, Luo, Xiangdong, Jang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006900/
https://www.ncbi.nlm.nih.gov/pubmed/24788909
http://dx.doi.org/10.1371/journal.pone.0096085